New hope for curing lung cancer: a strong predictor of resistance to immunotherapy just discovered
12 / 22 / 2023
12 / 12 / 2023
12 / 04 / 2023
Considering the importance of dendritic cells in fine-tuning T cell response, their manipulation represents an attractive approach to elicit or boost an anti-tumor immune response. To this end, we have developed and validated a mixed leukocyte reaction (MLR) assay to address DC function and evaluate their immune-modulatory properties.
10 / 23 / 2023
A Bessede, F Peyraud, S Le Moulec, S Cousin, M Cabart, F Chomy, C Rey, O Lara, O Odin, I Nafia, JP Guegan, A Italiano
10 / 18 / 2023
While mastering the key specifications of our macrophage-based models and their subtleties, our scientific and experimental expertise governs the relevance of our macrophage assays in evaluating the efficacy of immunotherapeutics either on the stimulatory M1 capacities or, especially, in relieving the suppressive functions of M2 macrophages.
09 / 18 / 2023