If, like our team, single-cell spatial transcriptomics has been on your wishlist for a while, well, it’s Christmas! We’re opening 3 slots (up to 4 slides each) with the human Immuno-Oncology panel on the 10x Xenium platform at a special price until the 20th of December (experiments will run in January).
What kind of information can you get with the Xenium IO panel from FFPE tumor samples?
- Tissue biology & architecture: identification of epithelial cells, fibroblasts, stromal cells, and tissue-specific markers
- Immune cell biology: accurate immune cell spatial typing (Ts, Bs, NKs, DCs, monocytes, macrophages, granulocytes) and single-cell information on key immune functions (antigen presentation, regulation, migration, checkpoint receptors, cytokines/chemokines)
- Cancer biology: identification of niches with specific tumor markers (immunogenicity, oncogenes, tumor suppressors, metastasis, immune evasion, DNA damage & apoptosis, metabolism, cell cycle, checkpoint ligands)
Neighborhood analysis shows distinct niches with different cell compositions
T cell exhaustion and tertiary lymphoid structure in breast DCIS
