The GeoMx Whole Transcriptome Atlas (WTA) empowers to explore biology accross a tissue. The human whole transcriptome (over 18,000 protein-coding human genes) is measured in each region of interest to uncover biological changes at specific locations of the tissue.
- Whole transcriptome coverage with probes specific to protein coding mRNA sequences
- Compatible with common sample types such as formalin-fixed paraffin embedded (FFPE) or fresh frozen (FF) tissue and across all human tissues types
- Superior sensitivity to detect 1000s of unique human genes in <50 μm regions
- Robust performance across sample types including FFPE with high concordance with RNA-seq and RNAscope™
- Map single cell RNA-seq populations to their tissue location
The GeoMx Whole Transcriptome Atlas delivers the maximum amount of sensitivity and confidence in each transcript through its unique probe architecture. The WTA profiles over 18,000 protein-coding human genes based on the human gene nomenclature committee (HUGO1) database cross-referenced with available mRNA sequences in the National Center for Biotechnology’s Information (NCBI) RefSeq database.
The WTA then allows to explore pathways across the whole transcriptome in defined regions of interest.