2024
- Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophosphamide. Molecular Cancer, 23(1), 38.
- Impact of metronomic trabectedin combined with low-dose cyclophosphamide on sarcoma microenvironment and correlation with clinical outcome: results from the TARMIC study. Molecular Cancer, 23(1), 37.
- Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study. Biomarker Research, 12(1), 3.
- TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non–Small Cell Lung Cancer. Clinical Cancer Research, 30(4), 779-785.
2023
- Upregulation of Indoleamine 2, 3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non–Small Cell Lung Cancer. Clinical Cancer Research, 29(23), 4883-4893.
- Standardized pathology screening of mature tertiary lymphoid structures in cancers. Laboratory Investigation, 103(5), 100063.
2022
- Pembrolizumab in soft-tissue sarcomas with tertiary lymphoid structures: a phase 2 PEMBROSARC trial cohort. Nature medicine, 28(6), 1199-1206.
- Indoleamine 2, 3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication. Immunity, 55(6), 1032-1050.
- Targeting tryptophan catabolism in cancer immunotherapy era: challenges and perspectives. Frontiers in immunology, 13, 807271.
- Regorafenib–avelumab combination in patients with biliary tract cancer (REGOMUNE): a single-arm, open-label, phase II trial. European Journal of Cancer, 162, 161-169.
- Randomized phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced soft-tissue sarcoma. Journal of Hematology & Oncology, 15(1), 149.
- Spatial transcriptomics of macrophage infiltration in non-small cell lung cancer reveals determinants of sensitivity and resistance to anti-PD1/PD-L1 antibodies. Journal for ImmunoTherapy of Cancer, 10(5).
- Trabectedin plus durvalumab in patients with advanced pretreated soft tissue sarcoma and ovarian carcinoma (TRAMUNE): an open-label, multicenter phase Ib study. Clinical Cancer Research, 28(9), 1765-1772.
- Pembrolizumab combined with low-dose cyclophosphamide and intra-tumoral injection of the toll-like receptor 4 agonist G100 in patients with advanced pretreated soft tissue sarcoma: results from the PEMBROSARC basket study. Journal of Hematology & Oncology, 15(1), 157.
- Phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced breast cancer. Experimental Hematology & Oncology, 11(1), 104.
- Prophylactic and therapeutic effect of kynurenine for experimental autoimmune encephalomyelitis (EAE) disease. International Journal of Tryptophan Research, 15, 11786469221118657.
- Impact of acetaminophen on the efficacy of immunotherapy in cancer patients. Ann Oncol. 33(9):909-915.
- Circulating L-arginine predicts the survival of cancer patients treated with immune checkpoint inhibitors. Ann Oncol. 33(10):1041-1051. doi: 10.1016/j.annonc.2022.07.001. Epub 2022 Jul 16. PMID: 35850444.
2021-2018
- Plasma proteomics identifies leukemia inhibitory factor (LIF) as a novel predictive biomarker of immune-checkpoint blockade resistance. Ann Oncol., 32(11):1381-1390.
- Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expression. Nature Cancer, 2(8), 794-802.
- Regorafenib-avelumab combination in patients with microsatellite stable colorectal cancer (REGOMUNE): a single-arm, open-label, phase II trial. Clinical Cancer Research, 27(8), 2139-2147.
- CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells. iScience, 24(11).
- CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism. iScience. 24(12)
- Cabozantinib in patients with advanced Ewing sarcoma or osteosarcoma (CABONE): a multicentre, single-arm, phase 2 trial. The lancet oncology, 21(3), 446-455.
- IDO targeting in sarcoma: biological and clinical implications. Frontiers in Immunology, 11, 274.
- Inactivating mutations in genes encoding for components of the BAF/PBAF complex and immune-checkpoint inhibitor outcome. Biomarker Research, 8(1), 26.
- Use of PD-1 targeting, macrophage infiltration, and IDO pathway activation in sarcomas: a phase 2 clinical trial. JAMA oncology, 4(1), 93-97.
- Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma. Nature communications, 9(1), 4775.
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ASCO 2023 TROP2 expression and response to immune checkpoint inhibition in patients with advanced non-small cell lung cancer
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