Quantitative in vitro assays for pharmacological characterization of PD1/PDL1 and CTLA4 immune checkpoint blockade
09 / 19 / 2018
We are offering an in vitro PD1/PDL1 blockade assay based on the high throughput HTRF measurement between PD1 and PDL1 partners. Our robust and easy-to-implement assay allows for consistent and reliable assessment of PD1 and/or PDL1 antibodies and modulatory agents, and can thus be used for screening campaigns, identification and functional assessment, as well as potency profiling of candidates.
Similar assays are also available for assessing the inhibition of CTLA4 interaction with B7-1 and B7-2 proteins - contact us for further information.
Comprehensive characterization could be also pursued through our range of complementary cell based assays.