Explicyte Immuno-Oncology - Cancer Immunotherapy CRO Services
Cancer Immunotherapy CRO Services
In vitro
Tumor killing
Tumor sensitization
Activation & immune checkpoint inhibition
Antibody-dependent cell cytotoxicity (ADCC)
Tumor antigen-specific killing
Immuno-modulation
Immune cell activation
Immune cell migration
Mixed lymphocyte reaction (MLR)
Macrophage assays
TLS-GC reaction
Cytokine release syndrome
In Vivo
Responsiveness to immunotherapies
PD-1/PD-L1 axis blockade
CTLA-4 blockade
Immunization
Syngeneic tumor models
Breast Cancer : 4T1
Breast Cancer : EMT6
Colon Cancer : CT26
Colon Cancer : MC38
Glioblastoma : GL261
Lung Cancer : Lewis LLC1
Pancreatic Cancer : Pan02
Renal Cancer : Renca
Sarcoma : MCA-205
Translational
Services
Custom tumor tissue sourcing
Target validation
Preclinical immune profiling
Biomarker discovery & testing
Image analysis
Technological platforms
Quantitative digital pathology
Digital spatial profiling
Single-cell spatial transcriptomics
Single-cell RNA Seq
Proteomics
Flow cytometry
Featured service
TLS detection & evaluation
Spatial transcriptomics
Single-cell analysis
Spatial biology
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Explicyte Immuno-Oncology
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Immune cell-mediated tumor killing assays
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TLS Detection & Scoring for Cancer Immunotherapy
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Syngeneic Tumor Models for the In Vivo Assessment Cancer Immunotherapies
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TLS Detection and Scoring by Digital Pathology
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In Vivo Models Of CTLA-4 Blockade
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In Vivo Models Of PD-1/PD-L1 Axis Blockade
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In Vivo immunization tumor models
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Biomarker Discovery & Testing for Immuno-Oncology
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Immune Response Profiling for Cancer Immunotherapies – Preclinical CRO Services
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Flow cytometry
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Proteomics
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RNA Sequencing
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