20+ colleagues
Explicyte is a human-sized company that brings cell biologists, immunologists, in vivo scientists, medical oncologists and bioinformaticians under the same roof.
High-tech platform
Spatial transcriptomics, advanced proteomics, digital pathology … Each year we invest ~15% of our turnover in research and instrumentation. Tech enthusiasts welcome!
Science with impact
Located in the Bergonié Comprehensive Cancer Center, we work in close relationship with clinicians and drug developers to advance novel immunotherapy strategies.
Contract type: Full time position, permanent contract
Location: Bordeaux, France
You are passionate about the interplay between immune and tumor cells? You have experience with 2D and 3D models? You master flow cytometry and other multiparametric platforms for in vitro analysis? The perspective of testing innovative cancer immunotherapies creates some excitement? Keep reading and apply!
Keep reading and apply!
About Explicyte
Explicyte is a preclinical and translational contract research organization specialized in immuno-oncology. Our goal is to assist academics, biotechs, and pharmas in the discovery of novel targets and novel cancer immunotherapies.
With a team of 25, we’re a human-sized company, which brings under the same roof cell biologists, immunologists, in vivo scientists, medical oncologists, and bioinformaticians. Focused on sponsors’ projects, our activity also involves in-house R&D and external collaborations, which led to the publication of 25+ papers in high-impact-factor journals.
Based in Bordeaux, our lab is located at the Bergonié Comprehensive Cancer Center, where we work in close contact with medical oncology teams. We believe Explicyte is a place to learn, grow, and have impact in the fight against cancer.
More about us
Your position
To strengthen and expand our in vitro team and activities, we are looking for an experienced in vitro Immuno-Oncology Scientist, ready to take up with us the setup of new in vitro platforms and assays, relevant for the testing and development of novel immunotherapeutic strategies.
In your role, you will be responsible for the technical and organizational management of sponsors’ and in-house R&D in vitro studies, from their implementation and performance to data analysis. You will timeously provide deliverables with respect to the project’s requirements and timelines.
You will interact closely with the in vitro team members, and will report to study directors and to the CSO.
What you will find at Explicyte
Your skills & traits
- Ph.D - or equivalent - in science and health-related field
- Minimum 2 years of experience in preclinical development in the health industry: Pharma, Biotech, CRO…
- Broad understanding of tumor immunology and/or cancer therapies
- Expertise in cell culture protocols (eg. 2D, 3D, immune/tumor cell co-cultures, immune cell isolation and cultivation, differentiation and polarization protocols)
- Mastery of multiparametric analysis methodologies, mainly in flow cytometry
- Project management experience (from planning to closing projects)
- Excellent diligence
- Strong interpersonal & organizational skills
- Ability to easily adapt to changing priorities and challenges
- Enthusiasm, curiosity, and integrity
Your missions & responsibilities
- Provide draft protocols according to the proposed scientific and experimental strategies
- Implement studies - relying on undeniable organizational skills - according to their design and established schedules
- Manage and perform - diligently - in vitro and ex-vivo experiments
- Cell culture-based experiments for functional immuno-oncology assays: with human and rodent cell origins, with tumor and/or immune cells (PBMCs, T cells, macrophages, tumor-infiltrating leukocytes…), and requiring immune cell isolation and cultivation, differentiation, polarization, etc
- 3D approaches: spheroids, organoids, and patient-derived tumor samples and their use in preclinical research and therapeutic assessment
- Ex vivo processing of collected samples for immune or tumor cell isolation, or for further analyses (FACS, ELISA…)
- Capture, analyze and compile data, including quality controls
- Ensure accuracy and completeness of study documentation and timely provide study deliverables
- Write internal protocols and standard operating procedures
- Contribute to experimental development by implementing new methods and training other collaborators and team’s members
Apply now!
Contract type: Full time position, permanent contract
Location: Bordeaux, France
You’re an accredited animal experimentalist with a passion for immune response mechanisms? You have experience with in vivo models for immuno-oncology? You master flow cytometry and other platforms for ex vivo analysis? The perspective of testing innovative cancer immunotherapies creates some excitement?
Keep reading and apply!
About Explicyte
Explicyte is a preclinical and translational contract research organization specialized in immuno-oncology. Our goal is to assist academics, biotechs, and pharmas in the discovery of novel targets and novel cancer immunotherapies.
With a team of 25, we’re a human-sized company, which brings under the same roof cell biologists, immunologists, in vivo scientists, medical oncologists, and bioinformaticians. Focused on sponsors’ projects, our activity also involves in-house R&D and external collaborations, which led to the publication of 25+ papers in high-impact-factor journals.
Based in Bordeaux, our lab is located at the Bergonié Comprehensive Cancer Center, where we work in close contact with medical oncology teams. We believe Explicyte is a place to learn, grow, and have impact in the fight against cancer.
More about us
Your position
To strengthen our in vivo preclinical activities, we are looking for an experienced in vivo Immuno-Oncology Study Manager, ready to take up with us the implementation of projects and their protocols, relevant for the testing and development of novel immunotherapeutic modalities.
In your role, you will be responsible for the technical and organizational management of sponsors’ and in-house R&D in vivo studies, from their implementation and performance to data analysis. You will timeously provide deliverables with respect to the project’s requirements and timelines.
You will closely interact with the in vivo team members. You will report to the Study Directors and CSO.
What you will find at Explicyte
Your skills & traits
- •Ph.D - or equivalent - in science and health-related field
- •Accreditation in animal experimentation level 1/2 is mandatory, ethical standards and regulations
- •Deep knowledge and mastery of preclinical tumor-bearing mouse models
- •Expertise in tissue collection and processing for flow cytometry-based analysis
- •Knowledge in the fields of tumor immunology and cancer therapies
- •Minimum 1-2 years’ experience in in vivopreclinical development in a health industry: Pharma, Biotech, CRO…
- •Project management experience (from planning to closing projects)
- •Excellent diligence
- •Strong interpersonal & organizational skills
- •Ability to easily adapt to changing priorities and challenges
- •Enthusiasm, curiosity, and integrity
Your missions & responsibilities
- Provide draft protocols according to the proposed scientific and experimental strategies
- Implement studies - relying on undeniable organizational skills - according to their design and established schedules
- Manage and perform - diligently - in vivo and ex vivo experiments
- Tumor cell line culture and maintenance
- Mastery of anesthesia and surgical gestures
- Tumor cell inoculation (subcutaneous, intradermic, intracranial, mammary fat pad, intrasplenic, etc.)
- In vivo monitoring: tumor growth (physical, bioluminescence), body weight and survival, tolerability evaluation
- Mastery of neuro-oncology related in vivo protocols and models is a plus
- Treatment administration (oral, intraperitoneal, intravenous, intratumoral)
- Sampling of biological tissues (blood, tumor, lymph nodes, organs)
- Ex vivo processing of collected samples for immune or tumor cell isolation, or for further analyses (FACS, ELISA…)
- Capture, analyze and compile data, including quality controls
- Ensure accuracy and completeness of study documentation and timely provide study deliverables
- Write and submit animal referrals for ethical committee approval
- Write internal protocols and standard operating procedures
Apply now!
2012-2014
ImmuSmol’s in vivo services
In 2012, freshly out of post-doc, immunologist Alban Bessede launched ImmuSmol, a biotech company developing antibodies against kynurenine pathway metabolites for diagnostic & therapeutic use. Building on Alban’s expertise in syngeneic tumor models treated with immune checkpoint inhibitors, ImmuSmol started to provide in vivo services on the side, to finance in-house R&D projects.
2015-2019
Launch of Explicyte Immuno-Oncology
In 2015, ImmuSmol launched a dedicated brand for ImmuSmol’s contract research activity in immuno-oncology: Explicyte. Adding capacities in in vitro screening and immune profiling (flow cytometry, digital pathology), Explicyte expanded its services to become a full-blown preclinical CRO. At the time, we company was located at the Biomedical Innovation Platform of the University of Bordeaux.
2020-2024
Pivot toward translational research
In 2020, the company moved to the Bergonié Comprehensive Cancer Center. Close collaboration with medical oncologists led the company to develop translational research projects and build a precision medicine platform. Scientific collaborations resulted in high-impact publications and team reinforcement with PhD & MDs.
We are the proud sponsors of the “Rugby Touch” team of the Institut Bergonié
Apply now !
Close to the city center of Bordeaux
We’re located at the Bergonié Institute (10 minute walk from the city center). You can go to work by train, tram or cycling. We take in charge 50% of your public transportation expenses.
A house with a garden !
In 2024, we moved to a freshly renovated house next to the Institut Bergonié. It’s a place for office work, meetings, lunchtime, and social events.
Young parents welcome
We arrange day-nursery for babies. And we are flexible in terms of working schedules, to make the life of young parents at little bit less challenging.
