20+ colleagues
Explicyte is a human-sized company that brings cell biologists, immunologists, in vivo scientists, medical oncologists and bioinformaticians under the same roof.
High-tech platform
Spatial transcriptomics, advanced proteomics, digital pathology … Each year we invest ~15% of our turnover in research and instrumentation. Tech enthusiasts welcome!
Science with impact
Located in the Bergonié Comprehensive Cancer Center, we work in close relationship with clinicians and drug developers to advance novel immunotherapy strategies.
Contract type: Full time position,fix-term contract
Location: Bordeaux, France
You like to play with large multi-omics datasets and analyze spatial information ? You have an interest in the biological processes involved in the response to cancer immunotherapies ? Keep reading and apply!
About Explicyte
Explicyte is a preclinical and translational contract research organization specialized in immuno-oncology. Our mission is to support academics, biotechs and pharmas in the discovery of novel targets and novel cancer immunotherapies.
With a team of 25, we’re a human-sized company, which brings under the same roof cell biologists, immunologists, medical oncologists and bioinformaticians. Focused on sponsors’ projects, our activity also involves in-house R&D and external collaborations, which led to the publication of 30+ papers in high impact-factor journals.
Based in Bordeaux, our lab is located at the Bergonié Comprehensive Cancer Center, where we work in close contact with medical oncology teams. We believe Explicyte is a place to learn, grow, and have impact in the fight against cancer.
More about us
Your position
To strengthen our translational research activities and benefit our partners, we are currently looking for an experienced Data Scientist.
In your role, you will be accountable for data mining & analysis in relation to sponsors’ and R&D studies. You will play with data from various biological samples (e.g. FFPE tumor samples, Peripheral Blood Mononuclear Cells, tumor immune infiltrates, plasmas, etc.), captured through a wide range of tools and platforms such as Immunohistochemistry (IHC)/Immunohistofluorescence (IHF), spatial transcriptomics, flow cytometry, gene expression profiling (RNAseq, TCRseq, scRNAseq) or proteomics and metabolomics.
You will interact with the translational team, and will report to the Chief Technology Officer.
What you will find at Explicyte
Your skills & traits
- Post-graduate degree (MSc/PhD) in computational biology, in bioinformatics, or biostatistics
- Strong experience in multi-omics data analysis, using genomic, transcriptomic, and other -omics datasets
- Proficiency in R programming language (markdown, shiny…) is mandatory. Other languages (Python, Groovy, mySQL…) are a plus
- Expertise in analysis softwares, such as Inform, Qupath, FlowJo, CellRanger
- Knowledge of basic and multivariate statistics is required
- Ability to conceptualize desired tables and graphs and codebase as needed
- Experience in cloud computing (AWS, Azure etc…) and database development (mySQL)
- Ability to adapt activities and priorities to challenging deliverables
- Fluency in written and oral English
- Good interpersonal and collaborative skills
Your missions & responsibilities
- Understand the biological issues and the questions asked
- Interact with the Data Science Director, the Study Managers or the collaborating teams for the optimal definition of the analysis criteria
- Collect, process, analyze and compare large-scale datasets from various origins (images, genomics, proteomics, metabolomics, etc.)
- Use pre-existing bioinformatics tools and develop new ones as needed to enable data mining and analysis (large-scale data analysis and integration, supervised or unsupervised learning, statistics, genomic analysis, modeling, deep learning, etc.)
- Provide documentation of procedures to describe the analytical strategies
- Run data analysis reports to support teams to provide study deliverables that meet project’s requirements and deadlines
- Have a theoretical understanding of data analysis algorithms, and be up to date with literature review to be at the forefront of developments in data analysis methods
Apply now!
2012-2014
ImmuSmol’s in vivo services
In 2012, freshly out of post-doc, immunologist Alban Bessede launched ImmuSmol, a biotech company developing antibodies against kynurenine pathway metabolites for diagnostic & therapeutic use. Building on Alban’s expertise in syngeneic tumor models treated with immune checkpoint inhibitors, ImmuSmol started to provide in vivo services on the side, to finance in-house R&D projects.
2015-2019
Launch of Explicyte Immuno-Oncology
In 2015, ImmuSmol launched a dedicated brand for ImmuSmol’s contract research activity in immuno-oncology: Explicyte. Adding capacities in in vitro screening and immune profiling (flow cytometry, digital pathology), Explicyte expanded its services to become a full-blown preclinical CRO. At the time, we company was located at the Biomedical Innovation Platform of the University of Bordeaux.
2020-2024
Pivot toward translational research
In 2020, the company moved to the Bergonié Comprehensive Cancer Center. Close collaboration with medical oncologists led the company to develop translational research projects and build a precision medicine platform. Scientific collaborations resulted in high-impact publications and team reinforcement with PhD & MDs.
We are the proud sponsors of the “Rugby Touch” team of the Institut Bergonié
Apply now !
Close to the city center of Bordeaux
We’re located at the Bergonié Institute (10 minute walk from the city center). You can go to work by train, tram or cycling. We take in charge 50% of your public transportation expenses.
A house with a garden !
In 2024, we moved to a freshly renovated house next to the Institut Bergonié. It’s a place for office work, meetings, lunchtime, and social events.
Young parents welcome
We arrange day-nursery for babies. And we are flexible in terms of working schedules, to make the life of young parents at little bit less challenging.
