Reference: SM0225
Contract type: Full time position, permanent contract
Location: Bordeaux, France
We are looking for an experienced in vitro Immuno-Oncology Scientist, ready to take up with us the setup and operation of 3D tumor model cultures, relevant for the testing and development of novel immunotherapeutic strategies.
In your role, you will be the scientific-technical referent in 3D cell culture, on all of R&D projects and Sponsors’ studies. You will interact with the in vitro team members.
You will have versatile & empowering missions. You will report to the Chief Scientific Officer.
What you will find at Explicyte
Explicyte is a preclinical and translational contract research organization specialized in immuno-oncology. Our goal is to assist academics, biotechs, and pharmas in the discovery of novel targets and novel cancer immunotherapies.
With a team of 25, we’re a human-sized company, which brings under the same roof cell biologists, immunologists, in vivo scientists, medical oncologists, and bioinformaticians. Focused on sponsors’ projects, our activity also involves in-house R&D and external collaborations, which led to the publication of 30+ papers in high-impact-factor journals.
Based in Bordeaux, our lab is located at the Bergonié Comprehensive Cancer Center, where we work in close contact with medical oncology teams. We believe Explicyte is a place to learn, grow, and have impact in the fight against cancer.
More about us
Contract type: Full time position, permanent contract
Location: Bordeaux, France
You are passionate about the interplay between immune and tumor cells? You have experience with 3D tumor-based culture models in the perspective of testing innovative cancer immunotherapies? You are proficient in flow cytometry and multiparametric platforms for in vitro/ex-vivo analyses? Keep reading and apply!
The position
We are looking for an experienced in vitro Immuno-Oncology Scientist, ready to take up with us the setup and operation of 3D tumor model cultures, relevant for the testing and development of novel immunotherapeutic strategies.
In your role, you will be the scientific-technical referent in 3D cell culture, on all of R&D projects and Sponsors’ studies. You will interact with the in vitro team members.
You will have versatile & empowering missions. You will report to the Chief Scientific Officer.
What you will find at Explicyte
Your skills & traits
- Post-graduate degree (MSc/PhD) in oncology, immuno-oncology, or related fields
- Expertise in 3D cell culture models and protocols (i.e. organoids, fragments, spheroids), with a minimum 3 years of experience
- Expertise in multiparametric analysis methodologies, e.g. flow cytometry, kinetic high content imaging, multiparametric supernatant analyses (LEGENDplex, Olink, etc), immunohistofluoresence
- Expertise in 2D cell culture protocols (immune/tumor cell co-cultures, immune cell isolation and cultivation, differentiation and polarization protocols)
- Proficiency in project management: from implementation and performance to data analysis and on time rendering of deliverables. Ability to manage multiple projects simultaneously
- Strong interpersonal & organizational skills
- Ability to easily adapt to changing priorities and challenges
- Fluency in written and oral English
Your missions & responsibilities
- Define, implement, and adapt adequate protocols according to the scientific purpose
- Provide draft protocols according to the scientific and experimental strategies
- Implement studies - relying on undeniable organizational skills - according to their design and established schedules
- Be responsible for handling and processing fresh tumor samples upon their receipt for their usability in 3D cultures
- Manage and perform - diligently - in vitro and ex-vivo experiments
- Cell culture-based experiments for functional immuno-oncology assays
- 3D tumor model cultures: organoids, tumor fragments, and spheroids, etc
- Ex vivo processing of collected samples for immune or tumor cell isolation, or for further analyses (FACS, ELISA…)
- Capture, analyze and compile data, including quality controls
- Ensure accuracy and completeness of study documentation and provide study deliverables on time
- Write internal protocols and standard operating procedures
- Contribute to experimental development by implementing new methods and training other collaborators and team’s members
About us
Explicyte is a preclinical and translational contract research organization specialized in immuno-oncology. Our goal is to assist academics, biotechs, and pharmas in the discovery of novel targets and novel cancer immunotherapies.
With a team of 25, we’re a human-sized company, which brings under the same roof cell biologists, immunologists, in vivo scientists, medical oncologists, and bioinformaticians. Focused on sponsors’ projects, our activity also involves in-house R&D and external collaborations, which led to the publication of 30+ papers in high-impact-factor journals.
Based in Bordeaux, our lab is located at the Bergonié Comprehensive Cancer Center, where we work in close contact with medical oncology teams. We believe Explicyte is a place to learn, grow, and have impact in the fight against cancer.
More about us
