The cancer immunotherapy blog

31 May In vitro immune cell-mediated killing

In vitro immune cell killing assay to assess your immunomodulatory candidate compounds/antibodies for their ability to enhance the killing immune response towards tumor cells. By using live cell imaging platform, our sensitive and quantitative assay based on 96-well plate co-culture of human tumor cells...

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14 Feb Orthotopic mouse model of Glioblastoma

Glioblastoma (GBM) is the most aggressive primary brain tumor. Despite multimodal treatment strategies with surgery, radiation therapy and chemotherapy, the prognosis of GBM patients remains dismal. GBM are characterized by a high immune cells infiltration including myeloid derived suppressor cells (MDSCs), microglia or regulatory T...

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12 Jul In vitro immune cell killing of tumor cells

Cancer immunoediting is a dynamic process which consists in three phases including elimination, equilibrium and tumor immune escape. During the elimination step there is an engagement of effector cells such as natural killer or T cells which initiate tumor cell death - an event defective...

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