Explicyte is a family brand of speciality preclinical services powered by the French company ImmuSmol. We provide contract research services through a range of validated in vitro assays and in vivo preclinical models to support innovative drug discovery programs.
Phenotypic & molecular screening assays in relevant cellular models
Well-characterized mouse models for in vivo efficacy & mechanism of action studies
Quantification of blood & tissue biomarkers in preclinical and clinical samples
Explicyte delivers preclinical CRO services in oncology and neuroscience. Based in Bordeaux, Explicyte is a brand of ImmuSmol. All our contract research services for drug discovery are performed at our laboratories, located in Pessac, France. However, we serve clients in the US, EU, UK, Germany, Canada and Switzerland. We assist biotechnology and pharmaceutical companies at different stages of non-clinical studies: in vitro cell-based assays (high-content screening), in vivo pharmacology and biomarker studies. In addition to our services for preclinical drug development, we offer bioanalytical services at clinical stages, for the analysis of blood biomarkers and tissue biomarkers - in the context of target validation or patient stratification. At earlier stages, we perform phenotypic screening campaigns for hit identification and lead characterization. We also have validated signaling pathway cellular assays for mechanism of action studies (MOA). Our capabilities extend to in vivo studies, using validated mouse models and relying on high-content imaging and flow cytometry (FACS) for in vivo drug profiling.